Answer

There is room to be lenient in certain cases, as the halakhic decisors wrote that with rabbinic prohibitions there is room to be lenient in a situation of need / distress / major loss. Each case depends on its own circumstances, and I cannot answer this in a general way.
But if I nevertheless have to give a general answer, I would say that we are obligated to overcome our distress and the obstacles within our psyche. As the Rif and the Rosh write in Moed Katan 16, that the law does not follow Rabbi Ilai (“let him wear black and do what his heart desires”), because everything is in the hands of Heaven except fear of Heaven. What pertains to fear of Heaven is in a person’s own hands, and he is obligated to overcome and not give in. But as stated, there are situations that may perhaps be regarded as great distress, in which one can be lenient.